Rash Decisions about Southern Tick--Associated Rash Illness and Lyme Disease

Rash decisions: Lyme disease, or not?

More than a syndrome, Lyme disease (Lyme borreliosis) is a specific tickborne zoonosis caused in North America by infection with a single spirochetal agent, Borrelia burgdorferi sensu stricto [1]. Natural transmission cycles of B. burgdorferi involve various rodents as principal reservoirs of infection and distinct species of hard ticks in the Ixodes ricinus complex as vectors. In the Northeast...

First culture isolation of Borrelia lonestari, putative agent of southern tick-associated rash illness.

Southern tick-associated rash illness (STARI) is a Lyme disease-like infection described in patients in the southeastern and south-central United States, where classic Lyme disease is relatively rare. STARI develops following the bite of a lone star tick (Amblyomma americanum) and is thought to be caused by infection with an "uncultivable" spirochete tentatively named Borrelia lonestari. In thi...

Southern Tick-Associated Rash Illness (STARI) in the North: STARI following a tick bite in Long Island, New York.

The most common clinical manifestation of Lyme disease is the characteristic rash, erythema migrans (EM). In the 1980s EM-like eruptions were reported in Missouri and other southeastern states. The EM-like eruptions, which were of unknown etiology, often followed the bite of the Lone Star tick (Amblyomma americanum) and the rash is called STARI (southern tick-associated rash illness). Although ...

[On the railway accident in Kastel-Stari].

Glucagonoma-Associated Rash.

A 65-year-old man with type 2 diabetes and deterioration of glycemic control presented with a 2-to-3-month history of weight loss (7 to 8 kg), early satiety, and mild flank pain. Before the occurrence of these symptoms, a rash had developed over the course of 3 to 4 weeks. The rash involved the arms, genitals, and buttocks and had progressed to the legs (Panel A). Laboratory evaluation at prese...